Indikatoren für Methadontabletten ohne Rezept online Sie wissen sollten
Indikatoren für Methadontabletten ohne Rezept online Sie wissen sollten
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The following information describes dosages that are commonly used or recommended. However, Beryllium sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.
Heart rhythm problems warning: This drug can cause serious heart rhythm problems, especially if you take doses greater than 200 Magnesium qua day. However, this can happen at any dose. It can even occur if you don’t already have heart problems.
Stopping methadone hydrochloride tablets. Ask your doctor for instructions on how to stop this medicine slowly to avoid uncomfortable symptoms. You should not stop taking methadone hydrochloride tablets all at once if you have been taking it for more than a few days.
Methadone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Particular vigilance is necessary during treatment initiation, during conversion from one opioid to another, and during dose titration.
The physician should not confuse such symptoms with those of narcotic abstinence and should not attempt to treat anxiety by increasing the dose of methadone. The action of methadone in maintenance treatment is limited to the control of narcotic withdrawal symptoms and is ineffective for relief of general anxiety.
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There may be new information. This leaflet does not take the place of talking with your doctor about your medical condition or your treatment. Share the important information in this leaflet with members of your household.
Patients should be cautioned that methadone, like all opioids, may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving or operating machinery.
Do not change your dose unless your doctor tells you to change it. Do not take a higher dose of methadone hydrochloride tablets or take it more often than prescribed. This can lead to an overdose and possibly death.
Overdose rein children warning: Children who accidentally take this drug have a high risk of death from overdosing. Children should not take this drug.
Do not take other medicines with methadone hydrochloride tablets without first talking with your doctor.
Methadone undergoes hepatic N-demethylation by cytochrome P-450 isoforms, principally CYP3A4, CYP2B6, CYP2C19, and to a lesser extent by CYP2C9 and CYP2D6. Coadministration of methadone with inducers of these enzymes may result in more rapid methadone metabolism, and potentially, decreased effects of methadone. Conversely, administration with CYP inhibitors may reduce metabolism and potentiate methadone's effects. Pharmacokinetics of methadone may be unpredictable when coadministered with drugs that are known to both induce and inhibit CYP enzymes.